Vitamin D deficiency aggravates ischemic acute kidney injury in rats
نویسندگان
چکیده
منابع مشابه
Vitamin D deficiency aggravates ischemic acute kidney injury in rats
Vitamin D deficiency (VDD) increases the risk of death in hospitalized patients. Renal ischemia/reperfusion injury (IRI) induces acute kidney injury (AKI), which activates cell cycle inhibitors, including p21, a cyclin-dependent kinase inhibitor and genomic target of 25-hydroxyvitamin D, which is in turn a potent immunomodulator with antiproliferative effects. In this study, we assess the impac...
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Reductions in renal microvasculature density and increased lymphocyte activity may play critical roles in the progression of chronic kidney disease (CKD) following acute kidney injury (AKI) induced by ischemia/reperfusion injury (IRI). Vitamin D deficiency is associated with tubulointerstitial damage and fibrosis progression following IRI-AKI We evaluated the effect of vitamin D deficiency in s...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2015
ISSN: 2051-817X
DOI: 10.14814/phy2.12331